Fection administration in high-risk individuals. P091 Risk factors and microbiological profile for nosocomial infections in trauma patients M. Ben Romdhane, Z. Douira, S. Kamoun, M. Bousselmi, A. Ben Souissi, Y. Boussarsar, A. Riahi, M.S. Mebazaa Mongi Trim University Clinic, La Marsa, Tunisia Essential Treatment 2016, 20(Suppl two):P091 Introduction: Nosocomial bacterial infections (NI) had been an important trigger of morbidity and mortality in trauma clients especially those hospitalized in ICU. The systemic inflammatory response that follows different lesions is responsible of immune dysfunction endorsing the emergence of pathogens and the occurrence of an infection. The intention of this study will be to discover risk elements for (NI), an infection web sites and microbiological profile in trauma clients. Procedures: We executed a retrospective examine inside the Intensive Care Unit of Mongi Slim Medical center La Marsa from January 2015 to September 2015. All Trauma clients hospitalized for additional than 48 hours at the ICU ended up provided. Demographic facts, kind and quantity of surgical procedures, usage of invasive equipment, days less than mechanical ventilation, site and quantity of NI have been recorded. We work out simple frequencies and relative frequencies (share) for qualitative variables. We work out suggests and regular deviations for quantitative variables. Benefits: A complete of 42 trauma sufferers were admitted for the duration of this nine month-period and twenty five sufferers developed no less than one particular NI. Contaminated people and non-infected just one was similar about gravity, and mortality. Contaminated clients essential more transfusions than noninfected types (Desk eleven). Contaminated individuals were being mainly involved with head trauma (73.8 ) and chest trauma (76.19 ). Ventilatory obtained pneumonia was the most frequent NI (seventy three.eight ). The most typical pathogens located were being Klebsiella Pneumoniae 31 , E Coli seventeen and Pseudomonas Aeroginosa eight.five . Clients with NI have experienced extra invasive gadgets. Conclusions: The infectious difficulties are definitely the next leading cause of late mortality right after mind damage. Accidents and invasive care promote pathogens penetration within the organism. This is exactly why, all trauma patients whose remain exceed 48 hrs, must profit from the quantity of set up early safety measures to stop infections specifically pneumonia.P092 Correlation in between percentages of ventilated people produced vap and usage of antimicrobial brokers in ICU sufferers. A. ROCK-IN-2 Vakalos, V. Avramidis Xanthi Normal Healthcare facility, Xanthi, Greece Vital Care 2016, 20(Suppl two):P092 Introduction: The intention of our observation retrospective research was to test PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/8627573 PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/22316373 the speculation that a correlation exists between the chances of ventilated people developed VAP as well as usage of main conclusion line antimicrobial brokers in ICU sufferers. Approaches: From 2008 to 2012 admitted to our ICU 384 individuals. We appeared for your share of ventilated sufferers designed VAP at the same time as the use of the subsequent brokers as products for every air flow working day for every ventilated individual: Imipenem / cilastatin (vial five hundred + 500 mg), Meropenem (vial a thousand mg), Tigecyclin (vial 50 mg), Linezoline (bag, 2 mg / ml x three hundred ml), Colistin IV (vial 106 IU). Employing linear correlation, we seemed for linear slope, correlation coefficient (r), coefficient of resolve (r2), r and p price. Success: Desk 12 Conclusions: According to our knowledge, there was no statistically important correlation detected in between the percentage of ventilated sufferers developed VAP and use of any of your conclude line antimicrobial agents studied. This will likely be owing to l.